Today’s blog post is
dedicated to my Anth 102 students, who were tasked with completing a service
learning assignment as part of their course requirements. For this assignment they were to create a
teaching/learning tool on a topic related to Mendelian Genetics. The following is my contribution to this
initiative.
Biology and culture intersect in a variety of different
ways. The most common means of
intersection is the cultural preference toward certain biological
characteristics. For example, blonde
hair and blue eyes is considered beautiful in many modern cultures, although
both characteristics are randomly inherited based on the alleles present in
each contributing parent. Much like
today, people in the past placed importance and preference on specific traits,
although they are not traits that most modern peoples would find
preferential. Today’s blog post will
explore ancient perceptions of specific genetic disorders, and the ancient
Egyptians, Olmec, and Inca will be the subject of this discussion.
Ancient Egyptians
& Achondroplasia
Achondroplasia, popularly known as “dwarfism”, is a genetic
disorder that presents as short stature and limbs in afflicted individuals. Achondroplasia is inherited through an
autosomal dominant chromosome, which means that individuals need only one copy
of the allele to have the condition.
This situation, where individuals carry only one copy of the
chromosome, is biologically favored as individuals who carry two copies typically
are stillborn or die shortly after birth.
This condition is caused by a mutation of a specific gene, known as the FGFR3 gene, and because of the this, it
is common for two individuals who do not have achondroplasia to produce a child
with achondroplasia. Because of the
automsomal dominance nature of this trait there is also an increased likelihood
that the offspring of two parents with achondroplasia will also have this
condition but could still produce offspring without the condition if they pass
on the recessive, non-affected chromosome.
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Figure 1: Bas relief of Bes, an Egyptian god with achondroplasia (Image Source) |
Views of those with achondroplasia do vary within modern
societies, although there is a history of them being treated poorly in American
culture. In ancient Egyptian culture,
individuals with achondroplasia were revered as evidenced by iconographic and
historical records. Their
condition was not considered a medical disorder based on the lack of mention of
the condition in Egyptian medical texts.
Individuals with achondroplasia were employed in special positions, such
as personal attendants to the Pharaohs and noble citizens, animal tenders,
jewelers, entertainers, and midwives.
This was because these individuals were considered to be manifestations
of the primary god, the Sun god, Ra. In
addition, two of the lesser gods, Ptah and Bes (Figure 1), were depicted with this
condition, further supporting the notion that individuals with achondroplasia
were celebrated. Overall, these
individuals were not shunned from society but instead embraced and celebrated.
Ancient Olmec and
Down’s Syndrome
Down’s syndrome is a genetic condition caused by having an
extra chromosome. Typically, humans have
46 chromosomes, but individuals with Down’s syndrome have an additional copy of
the 21st chromosome. It is
uncertain how specifically Down’s syndrome is passed on to offspring, but the
advanced age of the mother is believed to increase the likelihood of this
condition existing in offspring.
Individuals with Down’s syndrome typically have diminished intellect, as
well as physical features, including flattened faces, broad noses, slanted
eyes, shorter stature, and small hands and feet.
The Olmec culture existed in Central America from 1500 BC to
AD 300. It is a culture characterized by
various religious cults, the most prolific of which centered around the
jaguar. Jaguars were considered sacred
among the Olmec, a trend consistent with later cultures (e.g. the Maya and
Aztecs), and several jaguar-like sculptures have been discovered and are associated
with the culture. The most common is
that of a child with feline characteristics (Figure 2). Scholars analyzing the sculptures’ features have
identified similarities between them and the physical features of individuals
with Down’s Syndromes. Features in the sculpture
that are identified as being linked to Down’s syndrome include the slanted
eyes, puffy faces, downward drawn lower lips, and broad noses. It is believed that the Olmec believed that
individuals with Down’s syndrome were the offspring of jaguar-human sexual
relations, specifically that of a relationship between a jaguar-deity and human
woman, and therefore individuals with Down’s syndrome were held in high esteem.
Ancient Inca &
Cleft Lip
Cleft lip is the lack of fusion of the skin that makes up
the lip. Cleft lip can occur on either
side of the lip or in the center. There
is no common incidence of the location of the cleft lip. It is unclear what specifically causes cleft
lip, although it is believed that both genetic and environmental factors lead
to this condition. Individuals with
cleft lip often have problems eating, as well as deficiencies linked to proper
dental development.
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Figure 3: Inca Blackware pottery depicting cleft lip (Google Images) |
Individuals born with a cleft lip were believed to have been
blessed by lightning and therefore were considered godly and special among
ancient Inca people (Figure 3). Those with cleft
lip were reserved for special sacrificial rituals honoring lightning and sacred
mountain huacas (sacred places). This
may not seem like a benefit in our modern contexts, but to the Inca becoming a sacrifice
was a great honor, one reserved for a sacred few. While this practice is associated
specifically with the ancient Inca there is evidence of the veneration of
individuals with cleft palate occurring among earlier groups, such as the
Moche. It is believed that the Moche
identified individuals with cleft palate being the children of the lightning,
and these individuals were treated accordingly, with both admiration and
fear.
Bibliography
Dasen, V. 1988. “Dwarfism in Egypt and Classical Antiquity:
Iconography and Medical History.” Medical History 32: 253-276.
Kozma, C. 2006. “Historical Review: Dwarfs in Ancient Egypt.” American
Journal of Medical Genetics 140A: 303-311.
Milton, G. and R. Gonzalo.
1974. “Jaguar Cult—Down’s
Syndrome-Were-Jaguar.” Expedition 16: 33-35.
Murdy, CN. 1981. “Congenital Deformities and the Olmec
Were-Jaguar Motif.” American Antiquity 46: 861-871.
Reeves, C. 2001. Egyptian
Medicine. Shire Publication LTD:
Buckinghamshire.
Staller, J.E. and B. Stross.
2013. Lightning in the Andes and Mesoamerica: Pre-Columbian, Colonial, and
Contemporary Perspectives. Oxford
University Press: Oxford.