Over a decade ago it was discovered that contemporary human populations’ DNA was not solely their own. When Neanderthal DNA was sequenced it was quickly realized that they contributed DNA to anatomically modern Homo sapiens that existed contemporaneously with them. Since then it was discovered that contemporary human DNA also contains Denisovan DNA, as well as potentially other yet to be discovered hominid population’s DNA. A recent breakthrough in paleo-DNA studies, however, has cracked another code unexpectedly. Intermixture among closely related hominid groups did not occur recently but started over a million years ago.
Scholars from Cambridge University’s Department of Genetics sought to explore the genetic relationships among hominid ancestors. They knew from previous research that interbreeding was commonplace thousands of years ago, which begged the question as to if and when this may have occurred early. They analyzed data available through the 1000 Genomes Project and the Human Genome Diversity Project using a new method of their creation. This method, known as coalescence-based reconstruction of ancestral admixture (cobra), examines DNA to identify patterns of intermixture and separation among populations, and what they discovered was nothing short of remarkable.
They discovered that there were two ancestral hominid populations that split from each other 1.5 million years ago. They referenced the two populations as Population A and Population B. These populations remained genetically distinct from each other until 300,000 years ago, when they began interbreeding again. The interbred populations that came from the unions of Populations A & B eventually gave rise to modern humans, with Population A contributing 80% of its genetics to humans and Population B contributing 20%. The genetic contributions from Population B, albeit small, were incredibly important as these genes may have improved and enhanced brain function among modern human groups. There was a tradeoff, however. Complications in having children were also contributed.
At the present time it is unclear which hominid species made up the founders of Populations A & B. This is in part due to the lack of genetic evidence that can be collected from fossilized remains. The scholars hypothesize that the founding populations may have been Homo habilis or Homo heidelbergensis, but this is based on the timelines derived from the genetic data (as in H. habilis and H. heidelbergensis existed 1.5 million years ago). This is not a statement of fact.
Ultimately, these results demonstrate that interbreeding among hominid populations was not a recent phenomenon but one that occurred much earlier than originally known. It also opens up the potential to recognize that such relationships occurred among various hominid species. If this can be further scrutinized and identified then a more precise human lineage could be identified.
Bibliography
Cousins, T., Scally, A., & Durbin, R. (2025). A structured coalescent model reveals deep ancestral structure shared by all modern humans. Nature Genetics.
Killgrove, K. (2025, March 18). 'Mystery population' of human ancestors gave us 20% of our genes and may have boosted our brain function. Live Science.
StudyFinds Staff. (2025, March 18). Breakthrough DNA Analysis Reveals Everyone on Earth Shares Genes from Two Ancient Populations. Historical News, Study Finds.
University of Cambridge. (2025). Genetic study reveals hidden chapter in human evolution. Retrieved from University of Cambridge: https://www.cam.ac.uk/research/news/genetic-study-reveals-hidden-chapter-in-human-evolution