Sunday, April 13, 2014

It's All in the Family: Exploring Denisovans & Their Relationships to the Genus Homo



Note: Today is the blog's 1 year anniversary.  Thank you everyone for your support over the past year.  Please continue to enjoy the blog and this newer edition to physical anthropological knowledge.

The field of paleoanthropology is a dynamic one.  Paleoanthropologists focus their attentions on ancient human species and human evolution.  This is a difficult field due to the lack of concrete information available to scholars, which is in part why scholars are working diligently to uncover new evidence and to decipher it in relation to the currently known information.  New discoveries are continually being made, such as the discovery of the Denisovans, which has turned the discipline on its ear.

Figure 1: Denisovan finger fragment.

The Denisovans are a new species of the genus Homo discovered in 2008 in the Denisova Cave in Siberia, Russia.  This was an accidental discovery by Russian archaeologist Alexander Tsybankov who was excavating in 30,000 to 50,000 year old deposits.  He discovered the remnants of a finger bone (a distal phalange, end of a finger bone, to be exact, Figure 1).  He sent pieces of the bone to two researcher institutions for identification of the bone as well as further analyses, but it was the scholars at the Max Planck Institute who discovered that this finger bone did not belong to any known species-past or present.  They were able to recover mitochondrial DNA (mtDNA) and compared it to modern human and Neanderthal mtDNA in order to determine the association of the bone fragment, but the bone’s mtDNA matched neither species.  The scholars quickly realized that they had a newly discovered species on their, or rather its, hand.  

Figure 2: Denisovan molar
This discovery was further confirmed with the unearthing of two teeth that were later associated with this new species based on the teeth having the same mtDNA (Figure 2).  These teeth had been discovered prior to the finger fragment, but due to their large size, they were initially associated with belonging to an ancient bear species.  Taken together, these pieces of evidence confirmed the initial conclusion reached by the mtDNA evidence of the finger fragment.  The Denisova Cave had, at one point, been the home to a new, different species of the genus Homo that had not been discovered until that point.  The new species has been dubbed Denisovan, after the location of their unearthing.

But the breakthroughs did not end there.  Scholars at the Max Planck Institute managed to map the entire genome of Denisovan specimen, and they reached several interesting conclusions.  First, the finger fragment belonged to a young female child who was brown haired and eyed.  Second, Denisovans differed from other species in the genus Homo based on eight chromosomal differences, which allowed for significant skin and neurological differences that would account for potential morphological and physiological differences in the Denisovan species.  Third, the Denisovan DNA was very closely related to that of Homo neanderthalensis (Neanderthals) but also modern Homo sapiens, which suggested that Denisovans had sexual relations with both Neanderthals and humans.  Further analyses clarified that it was human females who selected for male Denisovans, hence how Denisovan genes ended up (and remain) in the modern human genome.  This conclusion was probably one of the most earth shattering of them all given the long held debate about whether or not humans and Neanderthals had sexual relations that produced offspring.

Further studies into Denisovans are ongoing, particularly excavations to discover more skeletal materials associated with the species.  While we have an idea of what the Denisovan DNA is, scholars have not yet determined the morphological appearance of the species, other than potential hair, eye, and skin colorings.  Future studies should not only assist in furthering the current understanding of the Denisovans but also the human lineage itself.  It will be interesting to see what else exists in the family tree of the genus Homo as further study continues. 

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